Breaking the Cycle of Addiction and Disease: Novel Strategies for Nicotine Cessation and Early Oral Cancer Screening

Ana Petrović

University of Novi Sad

Marko Jovanović

Department of Medicine, University of Niš

Keywords: Nicotine Addiction, Oral Cancer Screening, Cessation Strategies, Neurobiological Mechanisms, Novel Technologies, Early Detection


Abstract

Tobacco use, primarily through smoking, remains a leading cause of preventable death worldwide, contributing to a range of chronic diseases, including various cancers. Nicotine addiction perpetuates the cycle of tobacco use, while prolonged exposure to carcinogens in tobacco smoke increases the risk of oral and other cancers. This article provides a comprehensive review of current challenges and emerging strategies for nicotine cessation and early oral cancer screening. We discuss the neurobiological mechanisms underlying nicotine addiction, the limitations of existing cessation therapies, and novel approaches targeting the reward pathway and cognitive-behavioral interventions. Additionally, we explore the latest advancements in oral cancer screening techniques, including liquid biopsy, optical imaging, and artificial intelligence-assisted diagnostics. By integrating these complementary strategies, we aim to break the vicious cycle of addiction and disease, ultimately improving public health outcomes.


Author Biography

Marko Jovanović, Department of Medicine, University of Niš